Abstract
THE asexually proliferating larvae of the cestode Echinococcus multilocularis have an intriguing resemblance to malignant tumours. Indeed, until 1856 when Virchow demonstrated the parasitic nature of these cyst masses in man, such lesions were commonly diagnosed as carcinomas of the liver1. In the laboratory, infections with this parasite can be propagated vegetatively by transplanting the metacestode into the peritoneal cavity of susceptible rodent intermediate hosts2. The protoscolices transform into small cysts which grow and metastasise by peripheral herniation and the detachment of minute vesicles3.
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References
Virchow, R., Verh. Phys.-Med. Ges. Würzburg, 6, 84–95 (1856).
Lubinsky, G., Can. J. Zool., 38, 149–151 (1960).
Webster, G. A., and Cameron, T. W. M., Can. J. Zool., 34, 877–891 (1961).
Hibbs, J. B., Jr, Lambert, L. H., Jr, and Remington, J. S., J. Infect. Dis., 129, 587–592 (1971).
Hibbs, J. B., Jr, Lambert, L. H., Jr, and Remington, J. S., Nature new Biol., 235, 48–50 (1972).
Cleveland, R. P., Meltzer, M. S., and Zbar, B., J. natn. Cancer Inst., 52, 1887–1895 (1974).
Bluming, A. Z., Vogel, C. L., Ziegler, J. L., Mody, N., and Kamya, G., Ann. intern. Med., 76, 405–411 (1972).
Gutterman, J. U., Mavligit, G., McBride, C., Frei, E., and Hersh, E. M., Lancet, i, 1208–1212 (1973).
Rau, M. E., and Tanner, C. E., Can. J. Zool., 51, 55–59 (1973).
Baldwin, R. W., and Pimm, M. V., Br. J. Cancer, 30, 473–476 (1974).
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RAU, M., TANNER, C. BCG suppresses growth and metastasis of hydatid infections. Nature 256, 318–319 (1975). https://doi.org/10.1038/256318a0
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DOI: https://doi.org/10.1038/256318a0
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