Abstract
THE importance of cytoplasmic calcium has recently been emphasised by demonstrations that the ionophores X537A and A23187, which are known to facilitate the movement of Ca2+ through membranes1,2, trigger secretion in the presence of extracellular calcium ions3,4. We now report observations on the effects of these two cation ionophores on hen erythrocytes at physiological pH, which raise the possibility that the phenomenon of cell fusion may also be mediated by an increased concentration of cytoplasmic Ca2+.
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AHKONG, Q., TAMPION, W. & LUCY, J. Promotion of cell fusion by divalent cation ionophores. Nature 256, 208–209 (1975). https://doi.org/10.1038/256208a0
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DOI: https://doi.org/10.1038/256208a0
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