Abstract
WE report here the occurrence of somatic chromosome translocations in lymphocytes from individuals studied for clinical cytogenetic diagnosis. We note that these translocations are non-random in composition and resemble those in ataxia-telangiectasia (A-T) lymphocyte clones1. Our data have been collated with information from two other centres (Halifax and Atlanta) reported in this issue2,3 to provide a preliminary estimate of the frequency of chromosome translocations in cultured lymphocytes.
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References
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HECHT, F., McCAW, B., PEAKMAN, D. et al. [Letters to nature]. Nature 255, 243–244 (1975). https://doi.org/10.1038/255243a0
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DOI: https://doi.org/10.1038/255243a0
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