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Regulation of cell size in fish of tetraploid origin

Abstract

ALTHOUGH what precisely determines the characteristic size of the cell is still unknown its regulation must have been of enormous significance during evolution1,2. Bigger cells have a relatively lower metabolic rate than smaller ones so that the reduction of cell size is of adaptive value when changing environmental conditions requires an increase in metabolism and vice versa1,2. A decrease in cell size, however, must be accompanied by a corresponding loss of DNA if the nucleo–cytoplasmic relationship, which is fundamental in cell biology, is to be maintained.

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References

  1. Szarski, H., Nature, 226, 651–652 (1970).

    Article  ADS  CAS  Google Scholar 

  2. Bachmann, K., Goin, O. B., and Goin, G. J., in Evolution of Genetic Systems (edit. by Smith, H. H.), 419–450 (Gordon and Breach, New York, 1972).

    Google Scholar 

  3. Schmidtke, J., and Engel, W., Biochem. Genet. (in the press).

  4. Pedersen, R. A., J. exp. Zool., 177, 65–78 (1971).

    Article  CAS  Google Scholar 

  5. Siegel, A., Lightfoot, D., Ward, O. G., and Keener, S., Science, 179, 682–683 (1973).

    Article  ADS  CAS  Google Scholar 

  6. Maher, E. P., and Fox, D. P., Nature, 245, 170–172 (1973).

    CAS  Google Scholar 

  7. Ohno, S., Wolf, U., and Atkin, N. B., Hereditas, 59, 169–187 (1968).

    Article  CAS  Google Scholar 

  8. Birnstiel, M. L., Sells, B. H., and Purdom, J. F., J. molec. Biol., 63, 21–39 (1972).

    Article  CAS  Google Scholar 

  9. Bross, K., and Krone, W., Humangenetik, 14, 137–141 (1972).

    Article  CAS  Google Scholar 

  10. Loening, U. E., J. molec. Biol., 38, 355–365 (1968).

    Article  CAS  Google Scholar 

  11. Bachmann, K., Chromosoma (Berl.), 37, 85–93 (1972).

    Article  CAS  Google Scholar 

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SCHMIDTKE, J., ZENZES, M., DITTES, H. et al. Regulation of cell size in fish of tetraploid origin. Nature 254, 426–427 (1975). https://doi.org/10.1038/254426a0

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