Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

H1and H2 histamine receptors on Aplysia neurones

Abstract

WE have found two types of histamine receptor on neurones of the mollusc Aplysia corresponding to those already known in mammals. The presence of these specific receptors is consistent with the suggestion that histamine acts as a neurotransmitter.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Green, J. P., in Handbook of neurochemistry (edit. by Lajtha, J.), 4, 221–250 (Plenum, New York, 1970).

    Google Scholar 

  2. Ash, A. S. F., and Schild, H. O., Br. J. Pharmac. Chemother., 27, 427–439 (1966).

    Article  CAS  Google Scholar 

  3. Black, J. W., Duncan, W. A. M., Durant, C. J., Ganellin, C. R., and Parsons, E. M., Nature, 236, 385–390 (1972).

    Article  ADS  CAS  Google Scholar 

  4. Phillis, J. W., Tebecis, A. K., and York, D. H., Br. J. Pharmac. Chemother., 33, 426–440 (1968).

    Article  CAS  Google Scholar 

  5. Haas, H. L., Brain Res., 76, 363–366 (1974).

    Article  CAS  Google Scholar 

  6. Gargarg, M., Barbin, G., Feger, J., and Schwartz, J.-C., Science, 186, 833–835 (1974).

    Article  ADS  Google Scholar 

  7. Iorio, L. C., and McIsaac, R. J., J. Pharmac. exp. Ther., 151, 430–437 (1966).

    CAS  Google Scholar 

  8. Brimble, M. J., and Wallis, R. J., Nature, 246, 156–158 (1973).

    Article  ADS  CAS  Google Scholar 

  9. Kerkut, G. A., Walker, R. J., and Woodruff, G. N., Br. J. Pharmac. Chemother., 32, 241–252 (1968).

    Article  CAS  Google Scholar 

  10. Brownstein, M. J., Saavedra, J. M., Axelrod, J., Zeman, G. H., and Carpenter, D. O., Proc. natn. Acacl. Sci. U.S.A., 71, 4662–4665 (1974).

    Article  ADS  CAS  Google Scholar 

  11. Weinreich, D., Weiner, C., and McCaman, R., Brain Res. 84, 341–345 (1975).

    Article  CAS  Google Scholar 

  12. Carpenter, D. O., and Gaubatz, G. L., Nature, 252, 483–485 (1974).

    Article  ADS  CAS  Google Scholar 

  13. Kehoe, J., J. Physio., 225, 85–114 (1972).

    Article  CAS  Google Scholar 

  14. Carpenter, D. O., and Alving, B. O., J. gen. Physiol., 52, 1–21 (1968).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CARPENTER, D., GAUBATZ, G. H1and H2 histamine receptors on Aplysia neurones. Nature 254, 343–344 (1975). https://doi.org/10.1038/254343a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/254343a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing