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Structure of tobacco mosaic virus at 6.7 Å resolution

Naturevolume 254pages192196 (1975) | Download Citation

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Abstract

The electron density distribution of tobacco mosaic virus has been determined to 6.7 Å resolution by analysis of the X-ray diffraction pattern given by oriented gels of the virus. This has been achieved by separation of overlapping Bessel function terms by a technique analogous to crystallographic isomorphous replacement. The course of the polypeptide chain of the coat protein may be traced for a large part of its length.

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Author notes

    • E. Mandelkow

    Present address: The Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, 02154

Affiliations

  1. Max-Planck Institut fur Medizinische Forschung Abteilung Biophysik, 69 Heidelberg, Jahnstr., 29, West Germany

    • K. C. Holmes
    • , G. J. Stubbs
    • , E. Mandelkow
    •  & U. Gallwitz

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https://doi.org/10.1038/254192a0

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