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Structure of tobacco mosaic virus at 6.7 Å resolution

Abstract

The electron density distribution of tobacco mosaic virus has been determined to 6.7 Å resolution by analysis of the X-ray diffraction pattern given by oriented gels of the virus. This has been achieved by separation of overlapping Bessel function terms by a technique analogous to crystallographic isomorphous replacement. The course of the polypeptide chain of the coat protein may be traced for a large part of its length.

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Holmes, K., Stubbs, G., Mandelkow, E. et al. Structure of tobacco mosaic virus at 6.7 Å resolution. Nature 254, 192–196 (1975). https://doi.org/10.1038/254192a0

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