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Enhancement of the electrical excitability of neuroblastoma cells by valinomycin

Nature volume 254, pages 121–124 (1975)Cite this article

Abstract

Mouse neuroblastoma cells in stationary phase of growth display partially developed electrical properties. Addition of the K+ selective carrier valinomycin to these cells causes rapid enhancement of electrical excitability. We suggest that the appearance of molecules with properties similar to valinomycin is essential for the full expression of electrical excitability in differentiating neuroblastoma.

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Authors and Affiliations

  1. Department of Biochemistry, The Weizmann Institute of Science, Rehovot, Israel

    Ilan Spector, Clive Palfrey & Uriel Z. Littauer

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  1. Ilan Spector
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  2. Clive Palfrey
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  3. Uriel Z. Littauer
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Spector, I., Palfrey, C. & Littauer, U. Enhancement of the electrical excitability of neuroblastoma cells by valinomycin. Nature 254, 121–124 (1975). https://doi.org/10.1038/254121a0

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