Letter | Published:

Effect of a protein-free diet on lymph node and spleen cell response in vivo to blastogenic stimulants

Naturevolume 254pages6365 (1975) | Download Citation



A PROTEIN-deficient diet determines an early involution of the thymus, and the quantitative difference between lymphocytes from blood, lymph node and spleen of intact and of thymectomised rats is generally smaller with a protein deficient diet than with a normal one1,2. On the other hand, the decrease in the size of blood lymphocytes1, and in the viability3 of lymphocytes from lymph node and spleen, following deprivation of dietary protein is conditioned to a large extent by the atrophy of the thymus.

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  1. Centre National de la Recherche Scientifique, Centre Marcel Delépine, Laboratoire d'Hématologie nutritionnelle, 45045, Orléans Cedex, France



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