Abstract
EXPERIMENTS described here show that a large number of indirect, presumably IgG, plaque-forming cells (PFC) appear within a few hours during the initial stages of the IgG response of BALB/c mice to sheep red cells. When washed spleen cells are placed in vitro over the appropriate period indirect PFC develop as well as in vivo, but a few hours earlier.
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ADDISON, I. Sudden appearance of IgG plaque-forming cells. Nature 254, 61–62 (1975). https://doi.org/10.1038/254061a0
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DOI: https://doi.org/10.1038/254061a0
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