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Determinant of cistron specificity in bacterial ribosomes

Naturevolume 254pages3438 (1975) | Download Citation

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Abstract

The sequence of the 3′-terminus of 16S RNA from different bacteria has been determined. Complementarity relationships between this sequence and a purine-rich tract in the ribosome binding site of different bacterial mRNAs suggest that the 3′-end of 16S RNA determines the intrinsic capacity of ribosomes to translate a particular cistron.

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Affiliations

  1. Department of Biochemistry, School of General Studies, Australian National University, Canberra, ACT, 2600, Australia

    • J. Shine
    •  & L. Dalgarno

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https://doi.org/10.1038/254034a0

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