THE existence of differential chromosome contraction1–3 presents difficulties for morphometric chromosome analysis. Spiralisation rates of all the chromosomes change simultaneously4, and the sizes of all the chromosomes in the set must be correlated with one another, and also with the extent of contraction; the latter may be expressed as the total complement length (the total length of the chromosome complement).
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IORDANSKY, A., DERYAGUIN, G., BADAEV, N. et al. Influence of differential chromosome spiralisation on karyotype morphology. Nature 253, 734–735 (1975). https://doi.org/10.1038/253734a0
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