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Infection of differentiating muscle cells with influenza and Newcastle disease viruses


REPLICATION of influenza viruses is believed to require functions provided by the host cell nucleus because first, influenza replication is inhibited by actinomycin D and α amanitin, which prevent transcription of complementary RNA from virion RNA in the first few hours following infection1–4; and second, migration of viral proteins between host cell cytoplasm and nucleus occurs during the virus replicative cycle5–8.

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O'NEILL, M., KENDAL, A. Infection of differentiating muscle cells with influenza and Newcastle disease viruses. Nature 253, 195–198 (1975).

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