Abstract
THE function of the two populations of sensory cells in the mammalian inner ear is not well understood. Anatomical evidence indicates that the inner hair cells (IHCs) and the outer hair cells (OHCs) play separate roles in the transduction of acoustic stimuli1. Furthermore, there have been numerous proposals attributing different roles to the two hair cell populations in the production of the various cochlear potentials2–5. On the other hand, theoretical considerations and the interpretation of data from several experiments have led to suggestions of different types of interaction between the OHCs and IHCs6–8.
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References
Spoendlin, H., in Facts and Models in Hearing (edit. by Zwicker, E., and Terhardt, E.), 18–32, (Springer, New York, 1974).
Dallos, P., Billone, M., Durrant, J., Wang, C.-y., and Raynor, S., Science, 177, 356–358 (1972).
Davis, H., Deatherage, B. H., Rosenblut, B., Frenandez, C., Kimura, R., and Smith, C., Laryngoscope, 68, 596–627 (1958).
Kiang, N. Y.-s., Moxon, E. C., and Levine, R. A., in Sensorineural Hearing Loss (edit. by Wolstenholme, G. E. W., and Knight, J.), 241, (J. A. Churchill, England, 1970).
Dallos, P., and Wang, C.-y., Audiology, 13, 277–289 (1974).
Evans, E. F., in Facts and Models in Hearing (edit. by Zwicker, E., and Terhardt, E.), 118–129, (Springer, New York, 1974).
Lynn, P. A., and Sayers, B.McA., J. acoust. Soc. Am., 47, 525–532 (1970).
Zwislocki, J., and Sokolich, W. G., in Facts and Models in Hearing (edit. by Zwicker, E., and Terhardt, E.), 107–117, (Springer, New York, 1974).
Hawkins, J. E., and Engström, H., Acta oto-lar., suppl. 188 (1964).
Kohonen, A., Acta oto-lar., suppl. 208 (1965).
Miller, J., J. acoust. Soc. Am., 48, 513–523 (1970).
Engström, H., Ades, H., and Andersson, A., Structural Pattern of the Organ of Corti (Williams and Wilkins, Baltimore, 1966).
Bohne, B. A., (thesis, Univ. Washington, St. Louis 1971).
J., Wersäll, in Basic Mechanisms in Hearing (edit. by Moller, A.), 235 (Academic Press, New York, 1973).
Eldredge, D. H., Mills, J. H., and Bohne, B. A., Adv. oto-rhino-lar., 20, 64–81 (1973).
Elliot, D. N., and McGee, T. M., Anal. Otol., 74, 386–408 (1965).
Ward, W. D., and Duvall, A. J., Anal. Otol., 80, 881–896 (1971).
Hunter-Duvar, I. M., and Bredberg, G., J. acoust. Soc. Am., 55, 795–801 (1974).
Spoendlin, H., in Basic Mechanisms in Hearing (edit. by Moller, A.), 185 (Academic Press, New York, 1973).
Kiang, N.Y.-s., Watanabe, T., Thomas, F. C., and Clark, L. F., Discharge Patterns of Single Fibres in the Cat's Auditory Nerve (MIT Press, Cambridge, Mass., 1965).
Perkins, R., Anat. Rec., 175, 410 (1973).
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RYAN, A., DALLOS, P. Effect of absence of cochlear outer hair cells on behavioural auditory threshold. Nature 253, 44–46 (1975). https://doi.org/10.1038/253044a0
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DOI: https://doi.org/10.1038/253044a0
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