Abstract
THE ribosomal RNA (rRNA) molecules both of prokaryotes and of eukaryotes are not the immediate products of DNA transcription. Rather, precursors of the mature RNA species undergo a series of nucleotide modifications and/or cleavage events1,2. Only limited information is available concerning the mechanics of and rationale for post-transcriptional tailoring of RNA because of the large sizes of the precursor molecules and consequent difficulty in evaluating their nucleotide sequences.
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SOGIN, M., PACE, N. In vitro maturation of precursors of 5S ribosomal RNA from Bacillus subtilis. Nature 252, 598–600 (1974). https://doi.org/10.1038/252598a0
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DOI: https://doi.org/10.1038/252598a0
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