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The coenzyme-binding domains of glutamate dehydrogenases

Abstract

A combination of secondary structure predictions and sequence comparisons with dehydrogenases of known structure allows two coenzyme-binding domains to be located in each of the sequences of bovine and Neurospora glutamate dehydrogenases. One domain shows significant sequence homology with the structurally-similar domain of glyceraldehyde-3-phosphate dehydrogenase.

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Wootton, J. The coenzyme-binding domains of glutamate dehydrogenases. Nature 252, 542–546 (1974). https://doi.org/10.1038/252542a0

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