Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Replication of oncornavirus-like particle in human breast carcinoma cell line, MCF-7

Abstract

THE search for RNA-containing human breast cancer viruses has been helped by the discovery of several biochemical and biophysical characteristics of the oncornavirus group1–4. Although these properties may not be unique to oncornaviruses5, they provide biological reagents for more discriminating tests6–8 to establish species of origin, natural history and virus taxonomy for candidate viruses exhibiting these properties.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Schlom, J., and Spiegelman, S., Science, 174, 804–843 (1971).

    Article  Google Scholar 

  2. Schlom, J., Colcher, D., Spiegelman, S., Gillespie, S., and Gillespie, D., Science, 179, 696–698 (1973).

    Article  ADS  CAS  Google Scholar 

  3. Schlom, J., Spiegelman, S., and Moore, D. H. Nature, 231, 97–100 (1971).

    Article  ADS  CAS  Google Scholar 

  4. Feldman, S., Schlom, J., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 70, 1976–1980 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Harter, D. H., Axel, R., Burney, A., Gulati, S., Schlom, J., and Spiegelman, S., Virology, 52, 287–291 (1973).

    Article  CAS  Google Scholar 

  6. Ruprecht, R. M., Goodman, N. C., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 70, 1437–1441 (1973).

    Article  ADS  CAS  Google Scholar 

  7. Neiman, P. E., Nature new Biol., 244, 62–64 (1973).

    Article  CAS  Google Scholar 

  8. Axel, R., Gulati, S. C., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 69, 3133–3137 (1972).

    Article  ADS  CAS  Google Scholar 

  9. Axel, R., Schlom, J., and Spiegelman, S., Nature, 235, 32–36 (1972).

    Article  ADS  CAS  Google Scholar 

  10. Furmanski, P., Longley, C., Fouchey, D., Rich, R., and Rich, M. A., J. natn. J. Cancer Inst., 52, 975–977 (1974).

    Article  CAS  Google Scholar 

  11. Viola, M. V., J. natn. Cancer Inst., 50, 1175–1178 (1973).

    Article  CAS  Google Scholar 

  12. McGrath, C. M., Nandi, S., and Young, L., J. Virol., 9, 367–376 (1972).

    CAS  PubMed  PubMed Central  Google Scholar 

  13. McGrath, C. M., J. natn. Cancer Inst., 47, 455–467 (1971).

    CAS  Google Scholar 

  14. Soule, H. D., Vasquez, J., Long, A., Albert, S., and Brennan, M., J. natn. Cancer Inst., 51, 1409–1416 (1973).

    Article  CAS  Google Scholar 

  15. Brooks, S. C., Locke, E. R., and Soule, H. D., J. biol Chem., 248, 6251–6253 (1973).

    CAS  PubMed  Google Scholar 

  16. McCaffrey, R., Smoler, D. F., and Baltimore, D., Proc. natn. Acad. Sci. U.S.A., 70, 521–525 (1973).

    Article  ADS  CAS  Google Scholar 

  17. Blüthmann, H., Brück, D., Hübner, L., and Schöffski, A., Biochem. biophys. Res. Commun., 50, 91–97 (1973).

    Article  Google Scholar 

  18. Peterson, W., Stulberg, C., and Simpson, W., Proc. Soc. exp. Biol. Med., 136, 1187–1191 (1971).

    Article  CAS  Google Scholar 

  19. Soule, H., and Arnold, W., J. natn. Cancer Inst., 45, 253–262 (1970).

    CAS  Google Scholar 

  20. Oroszlan, S., Bova, D., Toni, R., and Gilden, R., Science, 176, 420–422 (1972).

    Article  ADS  CAS  Google Scholar 

  21. Varmus, H. E., et al., J. molec. Biol., 79, 663–679 (1973).

    Article  CAS  Google Scholar 

  22. Bassin, R., Tuttle, N., and Fishinger, P., Nature, 229, 564–566 (1971).

    Article  ADS  CAS  Google Scholar 

  23. Black, M. M., et al., Cancer Res., 34, 1054–1060 (1974).

    CAS  PubMed  Google Scholar 

  24. Cardiff, R. D., J. Immun., 111, 1722–1727 (1973).

    CAS  PubMed  Google Scholar 

  25. McCormick, J. J., and Calhoun, L., J. analyt., Biochem., 54, 54–57 (1973).

    Article  CAS  Google Scholar 

  26. McGrath, C. M., and Blair, P. B., Cancer Res., 30, 1963–1968 (1970).

    CAS  PubMed  Google Scholar 

  27. Soule, H. D., Maloney, T., Vasquez, J., and Long, A., Proc. Am. Ass. Cancer Res., 14, 90 (1973).

    Google Scholar 

  28. Reitz, M. S., Abrell, J. W., Tracnov, C., and Gallo, R. C., Biochem. biophys. Res. Commun., 49, 30–38 (1972).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MCGRATH, C., GRANT, P., SOULE, H. et al. Replication of oncornavirus-like particle in human breast carcinoma cell line, MCF-7. Nature 252, 247–250 (1974). https://doi.org/10.1038/252247a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/252247a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing