Reaction of human smooth muscle antibodies with human blood lymphocytes and lymphoid cell lines


ANTIBODIES to smooth muscle appear in serum from cases of active chronic hepatitis1,2 and transiently in various acute viral diseases3,4. The smooth muscle antibodies (SMA) are demonstrated by indirect immunofluorescence (IFL) using cryostat sections of rat stomach and kidney and human thyroid5. The reaction of SMA-positive sera with lymphoid tissue has been pointed out6,7. Here we deal with the reaction of SMA in indirect IFL on human peripheral lymphocytes and especially with lymphoblastoid cell lines.

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FAGRAEUS, A., LIDMAN, K. & BIBERFELD, G. Reaction of human smooth muscle antibodies with human blood lymphocytes and lymphoid cell lines. Nature 252, 246–247 (1974).

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