Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Liposomes can mimic virus membranes

Abstract

CONSIDERABLE insight into mechanisms of membrane permeability and transport has been obtained from the study of simple lipid membranes. For the study of membrane–membrane interactions, however, such model systems have been used to a much lesser extent. If present ideas that biological membranes possess extended areas of lipid bilayer are correct, then it is probable that bilayer regions are involved in intermembrane phenomena such as adhesion and fusion, and it becomes reasonable to use simple lipid membranes to mimic such behaviour.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Howell, J., and Lucy, J., FEBS Lett., 4, 147–150 (1969).

    Article  CAS  Google Scholar 

  2. Ahkong, Q., Cramp, F., Fisher, D., Howell, J., and Lucy, J., J. Cell Sci., 10, 769–787 (1972).

    CAS  PubMed  Google Scholar 

  3. Papahadjopoulos, D., Poste, G., and Schaeffer, B., Biochem. biophys. Acta., 323, 23–42 (1973).

    Article  CAS  Google Scholar 

  4. Grant, C., and McConnell, H., Proc. natn. Acad. Sci. U.S.A., 70, 1238–1240 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Bangham, A., Standish, M., and Watkins, J., J. molec. Biol., 13, 238–252 (1965).

    Article  CAS  Google Scholar 

  6. Miyamoto, V., and Stoeckenius, W., J. Memb. Biol., 4, 252–269 (1971).

    Article  CAS  Google Scholar 

  7. Bangham, A., Flemans, R., Heard, D., and Seaman, F., Nature, 182, 642–644 (1958).

    Article  ADS  CAS  Google Scholar 

  8. Johnson, M., Simon, S., Kauffman, J., and MacDonald, R., Biochem. biophys. Acta., 291, 587–591 (1973).

    Article  CAS  Google Scholar 

  9. Hanahan, D., Rodbell, M., and Turner, L., J. biol. Chem., 206, 431–441 (1954).

    CAS  PubMed  Google Scholar 

  10. Okada, Y., Murayama, F., and Yamada, K., Virology, 28, 115–130 (1966).

    Article  CAS  Google Scholar 

  11. Salk, J., J. Immun., 49, 87–98 (1944).

    Google Scholar 

  12. Neurath, A., and Sokol, F., Acta Virologica, 6, 66–75 (1962).

    CAS  Google Scholar 

  13. Neurath, A., Verneer, S., Hartzell, R., and Rubin, B., J. gen. Virol., 16, 245–249 (1972).

    Article  CAS  Google Scholar 

  14. Kohn, A., Virology, 26, 228–245 (1965).

    Article  CAS  Google Scholar 

  15. Morgan, C., and Howe, C., J. Virol., 2, 1122–1132 (1969).

    Google Scholar 

  16. Heine, J., and Schnaitman, C., J. Virol., 8, 786–795 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  17. Apostolov, K., and Almeida, J., J. gen. Virol., 15, 227–234 (1972).

    Article  CAS  Google Scholar 

  18. Zee, Y., and Talens, S., J. gen. Virol., 11, 59–63 (1971).

    Article  CAS  Google Scholar 

  19. Grandos, R., Virology, 52, 305–309 (1973).

    Article  Google Scholar 

  20. Razin, S., Biochim. biophys. Acta, 265, 241–296 (1972).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MARTIN, F., MACDONALD, R. Liposomes can mimic virus membranes. Nature 252, 161–163 (1974). https://doi.org/10.1038/252161a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/252161a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing