THERE is much physiological evidence that L-glutamate acts as an excitatory transmitter at many arthropod neuromuscular synapses1–3. The only suggestion that acetylcholine (ACh) has such a function is due to Futamachi4. He showed that the nerve terminal region innervated by the largest crayfish slow flexor excitatory motor neurone is depolarised by iontophoretic applications of ACh, but not L-glutamate. I now have biochemical and physiological evidence that ACh is the neurotransmitter at some, but not all, of the excitatory neuromuscular synapses of the lobster stomatogastric system.
This is a preview of subscription content, access via your institution
Subscribe to Journal
Get full journal access for 1 year
only $3.90 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Tax calculation will be finalised during checkout.
Get time limited or full article access on ReadCube.
All prices are NET prices.
Takeuchi, A., and Takeuchi, N., J. Physiol., 170, 296–317 (1964).
Beránek, R., and Miller, P. I., J. exp. Biol., 49, 83–93 (1968).
Usherwood, P. N. R., and Machili, P., J. exp. Biol., 49, 341–361 (1968).
Futamachi, K. J., Science, 175, 1373–1375 (1972).
Maynard, D. M., and Dando, M. R., Phil. Trans. R. Soc. London, ser. B, 268, 161–220 (1970).
Maynard, D. M., Ann. N.Y. Acad. Sci., 193, 59–72 (1972).
Mulloney, B., and Selverston, A. I., J. comp. Physiol., 91, 1–32 (1974).
McCaman, R. E., Weinreich, D., and Boyrs, H., J. Neurochem., 21, 473–476 (1973).
Giller, E., jun., and Schwartz, J. H., J. Neurophysiol., 34, 93–107 (1971).
Coggeshall, R. E., Dewhurst, S. A., Weinreich, D., and McCaman, R. E., J. Neurobiol., 3, 259–265 (1972).
Marder, E., thesis, Univ. California, San Diego (1974).
Maynard, D. M., and Atwood, H. A., Am. Zool., 9, 1007 (1969).
About this article
Cite this article
MARDER, E. Acetylcholine as an excitatory neuromuscular transmitter in the stomatogastric system of the lobster. Nature 251, 730–731 (1974). https://doi.org/10.1038/251730a0
This article is cited by
Localization of neurons expressing choline acetyltransferase, serotonin and/or FMRFamide in the central nervous system of the decapod shore crab Hemigrapsus sanguineus
Cell and Tissue Research (2021)
The transient potassium outward current has different roles in modulating the pyloric and gastric mill rhythms in the stomatogastric ganglion
Journal of Comparative Physiology A (2017)
Motor pattern generation of the posterior cardiac plate-pyloric system in the stomatogastric ganglion of the mantis shrimp Squilla oratoria
Journal of Comparative Physiology A (1993)
Journal of Comparative Physiology A (1988)