Abstract
THERE is much physiological evidence that L-glutamate acts as an excitatory transmitter at many arthropod neuromuscular synapses1–3. The only suggestion that acetylcholine (ACh) has such a function is due to Futamachi4. He showed that the nerve terminal region innervated by the largest crayfish slow flexor excitatory motor neurone is depolarised by iontophoretic applications of ACh, but not L-glutamate. I now have biochemical and physiological evidence that ACh is the neurotransmitter at some, but not all, of the excitatory neuromuscular synapses of the lobster stomatogastric system.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Takeuchi, A., and Takeuchi, N., J. Physiol., 170, 296–317 (1964).
Beránek, R., and Miller, P. I., J. exp. Biol., 49, 83–93 (1968).
Usherwood, P. N. R., and Machili, P., J. exp. Biol., 49, 341–361 (1968).
Futamachi, K. J., Science, 175, 1373–1375 (1972).
Maynard, D. M., and Dando, M. R., Phil. Trans. R. Soc. London, ser. B, 268, 161–220 (1970).
Maynard, D. M., Ann. N.Y. Acad. Sci., 193, 59–72 (1972).
Mulloney, B., and Selverston, A. I., J. comp. Physiol., 91, 1–32 (1974).
McCaman, R. E., Weinreich, D., and Boyrs, H., J. Neurochem., 21, 473–476 (1973).
Giller, E., jun., and Schwartz, J. H., J. Neurophysiol., 34, 93–107 (1971).
Coggeshall, R. E., Dewhurst, S. A., Weinreich, D., and McCaman, R. E., J. Neurobiol., 3, 259–265 (1972).
Marder, E., thesis, Univ. California, San Diego (1974).
Maynard, D. M., and Atwood, H. A., Am. Zool., 9, 1007 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MARDER, E. Acetylcholine as an excitatory neuromuscular transmitter in the stomatogastric system of the lobster. Nature 251, 730–731 (1974). https://doi.org/10.1038/251730a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/251730a0
This article is cited by
-
Differential expression of neuropeptide F in the digestive organs of female freshwater prawn, Macrobrachium rosenbergii, during the ovarian cycle
Cell and Tissue Research (2024)
-
Localization of neurons expressing choline acetyltransferase, serotonin and/or FMRFamide in the central nervous system of the decapod shore crab Hemigrapsus sanguineus
Cell and Tissue Research (2021)
-
The transient potassium outward current has different roles in modulating the pyloric and gastric mill rhythms in the stomatogastric ganglion
Journal of Comparative Physiology A (2017)
-
Neuroscience: A gut feeling
Nature (2007)
-
Motor pattern generation of the posterior cardiac plate-pyloric system in the stomatogastric ganglion of the mantis shrimp Squilla oratoria
Journal of Comparative Physiology A (1993)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
