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Size and location of the transforming region in human adenovirus type 5 DNA


Fragments of human adenovirus type 5 DNA as small as one million daltons can transform cells in vitro. The DNA segment which induces transformation is located between 1 and 6% from the left end of the Ad 5 DNA molecule.

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Graham, F., van der Eb, A. & Heijneker, H. Size and location of the transforming region in human adenovirus type 5 DNA. Nature 251, 687–691 (1974).

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