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Polyanions and lipopolysaccharide acts on different subpopulations of B cells

Abstract

WITH respect to maturation stage, function, and cell surface constituents, lymphocytes bearing immunglobulin on their (B cells) comprise a heterogenous population. It has been suggested1 that binding of mitogens to membrane surface surface constituents triggers the events leading to stimulation of cell mitosis. The various B cell mitogens can be divided into different chemical classes and different types of mitogens presumably react with different membrane surface constituents. According to these assumptions we tested whether various B cell mitogens act on the same or on different subpopulations of B cells.

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References

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DIAMANTSTEIN, T., BLITSTEIN-WILLINGER, E. & SCHULZ, G. Polyanions and lipopolysaccharide acts on different subpopulations of B cells. Nature 250, 596–597 (1974). https://doi.org/10.1038/250596a0

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