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Restoration of specific immunological virginity

Abstract

The specific abrogation of an established immune response was studied by removing in vivo most of the immuno-competent lymphocytes reactive against the specific antigen, thus restoring the animal to a state of specific immunological virginity.

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McConnell, I., Lachmann, P. & Hobart, M. Restoration of specific immunological virginity. Nature 250, 113–116 (1974). https://doi.org/10.1038/250113a0

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