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Lithium and the monoamine neurotransmitters in the rat hippocampus

Nature volume 250, pages 71–73 (1974)Cite this article

Abstract

ALTHOUGH the psychoactive properties and therapeutic value of lithium have long been recognised1, relatively little is known about its mode of action in the central nervous system2. This is partly due to the lack of a complete understanding of the biological basis of mental disorders and to the variety of biological functions that can be affected by lithium.

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References

  1. Cade, J. F. J., Med. J. Aust., 36, 349 (1949).

    Article  Google Scholar 

  2. Samuel, D., and Gottesfeld, Z., Endeavour, 32, 122 (1973).

    CAS  PubMed  Google Scholar 

  3. Greenspan, K., Aronoff, M. S., and Bogdanski, D. F., Pharmacology, 3, 129 (1970).

    Article  CAS  Google Scholar 

  4. Ho, A. K. S., Loh, H. H., Craves, F., Hitzemann, R. J., and Gershon, S., Eur. J. Pharmac., 10, 72 (1970).

    Article  CAS  Google Scholar 

  5. Ungerstedt, U., Acta physiol. scand., 82 Suppl. 367, 1 (1971).

    Google Scholar 

  6. Segal, M., and Bloom, F. E., Brain Res., 72, 79 (1974).

    Article  CAS  Google Scholar 

  7. Segal, M., and Bloom, F. E., Brain Res., 72, 99 (1974).

    Article  CAS  Google Scholar 

  8. Salmoiraghi, G. C., and Weight, F. F., Anesthesiology, 28, 54 (1968).

    Article  Google Scholar 

  9. Bunney, W. E., Goodwin, F. K., Davis, J. M., and Fawcett, S. A., Am. J. Psychiat., 125, 444 (1968).

    Article  Google Scholar 

  10. Baer, L., Kassir, S., and Fiere, R., Psychopharmacologia, 17, 216 (1970).

    Article  CAS  Google Scholar 

  11. Siggins, G. R., Battenberg, F. F., Hoffer, B. J., and Bloom, F. F., Science, 179, 585 (1973).

    Article  ADS  CAS  Google Scholar 

  12. Forn, J., and Valdecasas, F. G., Biochem. Pharmac., 20, 2773 (1971).

    Article  CAS  Google Scholar 

  13. Colburn, R. W., Goodwin, F. K., Bunney, E. W., and Davis, J. M., Nature, 215, 1395 (1967).

    Article  ADS  CAS  Google Scholar 

  14. Katz, R. I., Chase, T. N., and Kopin, I. J., Science, 162, 466 (1968).

    Article  ADS  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Laboratory of Neuropharmacology, Special Mental Health Research Division IRP, National Institute of Mental Health, Saint Elizabeths Hospital, Washington, DC, 20032

    MENAHEM SEGAL

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  1. MENAHEM SEGAL
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SEGAL, M. Lithium and the monoamine neurotransmitters in the rat hippocampus. Nature 250, 71–73 (1974). https://doi.org/10.1038/250071a0

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