Letter | Published:

Rats learning to work for alcohol

Nature volume 249, pages 590592 (07 June 1974) | Download Citation

Subjects

Abstract

IF animals are to be used in the study of alcoholism, it is important that they show characteristics similar to human alcoholics. It has been demonstrated that animals can show tolerance and withdrawal symptoms to alcohol1: therefore, animals can legitimately be used to study these aspects. There has, however, been little evidence that animals develop the most important factor in alcoholism, a strong motivation to obtain alcohol for drinking. As there have been no demonstrations of animals learning a new response, or even continuing to make a previously learned response, to obtain drinking alcohol, in the presence of food and water ad libitum, it has been possible to claim that their alcohol consumption is ‘accidental and inadvertent’2. If this were true, experiments on voluntary alcohol drinking by animals would be of little value for generalising to humans.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , Pharmac. Biochem. Behav., 1, 89 (1973).

  2. 2.

    , and , Pharmac. Biochem. Behav., 1, 103 (1973).

  3. 3.

    , Science, 159, 739 (1968).

  4. 4.

    , Ann. Med. exp. Biol. Fenn., 49, 67 (1971).

  5. 5.

    , and , J. comp. physiol. Psychol., 84, 332 (1973).

  6. 6.

    , and , Q. Jl Stud. Alcohol., 25, 226 (1964).

  7. 7.

    , and , J. Psychiat. Res., 3, 145 (1965).

  8. 8.

    , and , in Biological Aspects of Alcohol Consumption (edit. by Forsander, O., and Eriksson, K.) (Finnisn Foundation for Alcohol Studies, Helsinki, 1971).

  9. 9.

    , and , Psychopharmacologia Laboratories, No. PR–71–2 (Department of Psychiatry, University of Minnesota, 1971).

  10. 10.

    , and , Psychopharmacologia (Berl.), 28, 171 (1973).

  11. 11.

    , , and , Psychopharmacologia (Berl.), 16, 30 (1969).

  12. 12.

    , and , in Alcoholism and the Central Nervous System (edit. by Seixas, F. A., and Eggleston, S.), Ann. N.Y. Acad. Sci., 215, 162 (193).

  13. 13.

    , , and , in Biological Aspects of Alcoholism (edit. by Roach, M. R., McIsaac, W. M., and Creaven, P. J.) (University of Texas Press, Austin, 1971).

  14. 14.

    , , and , 23rd Int. Congr. Physiol. Sci. (Abstr. No. 66) (Tokyo, 1965).

  15. 15.

    , in Biological Aspects of Alcohol Consumption (edit. by Forsander, O., and Eriksson, K.) (Finnish Foundation for Alcohol Studies, Helsinki, 1971).

Download references

Author information

Affiliations

  1. Research Laboratories, State Alcohol Monopoly (Alko), Box 350, Helsinki 10, Finland

    • J. D. SINCLAIR

Authors

  1. Search for J. D. SINCLAIR in:

About this article

Publication history

Received

Published

DOI

https://doi.org/10.1038/249590a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.