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Absence of adenine nucleotide release from autonomic ganglion

Abstract

SYNAPTIC vesicles isolated from Torpedo electroplaques contain ATP as well as acetylcholine (ACh)1,2. Silinsky and Hubbard3 showed that ATP is released from the rat hemidiaphragm bathed in a hyperosmotic medium and they suggested that the motor nerve terminal releases ACh and ATP simultaneously. Here we report tests for the release of ATP and ACh from the cat superior cervical ganglion; we demonstrated that ACh, but not ATP, is released during stimulation.

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KATO, A., KATZ, H. & COLLIER, B. Absence of adenine nucleotide release from autonomic ganglion. Nature 249, 576–577 (1974). https://doi.org/10.1038/249576a0

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