Abstract
ASSUMING that morphine induces dependence in response to continued interaction of the drug with an unidentified biochemical process of neurones, then suitable pharmacological manipulation might produce a paradigm of the morphine abstinence syndrome in experimental animals not exposed to any opiate. If so, the way in which such a quasi-abstinence syndrome was produced might throw light on the endogenous biochemical process involved1.
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COLLIER, H., FRANCIS, D., HENDERSON, G. et al. Quasi morphine-abstinence syndrome. Nature 249, 471–473 (1974). https://doi.org/10.1038/249471a0
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DOI: https://doi.org/10.1038/249471a0
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