Abstract
CELL surface components play a major role in the control of normal cell interactions and in the altered growth control and antigenic properties of malignant cells1. To characterise tissue-specific cell surface proteins we undertook an immunochemical study of the material released from cells by mild proteolytic treatment. Our studies have disclosed a fibroblast-specific cell surface and serum antigen in chicken2. The amount of this antigen is greatly reduced in chicken fibroblasts transformed by Rous sarcoma virus.
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RUOSLAHTI, E., VAHERI, A. Novel human serum protein from fibroblast plasma membrane. Nature 248, 789–791 (1974). https://doi.org/10.1038/248789a0
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DOI: https://doi.org/10.1038/248789a0
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