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Zinc ions inhibit replication of rhinoviruses


THE rhinoviruses comprise a subgroup of the picornaviruses, distinguished by their acid lability. They are medically important as the infectious agents of the common cold in man. Although there have been reports of chemical agents which inhibit rhinovirus replication, in only a few instances has the mode of antiviral action been demonstrated at a biochemical level1,2.

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KORANT, B., KAUER, J. & BUTTERWORTH, B. Zinc ions inhibit replication of rhinoviruses. Nature 248, 588–590 (1974).

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