Letter | Published:

Ion Fluxes in Disk Membranes of Retinal Rod Outer Segments

Naturevolume 247pages562563 (1974) | Download Citation

Subjects

  • An Erratum to this article was published on 03 May 1974

Abstract

THE process of transduction in vision is that mechanism whereby absorption of light by a photoreceptor cell in the retina results in a polarisation of the receptor cell membrane, excitation of the cell, and the eventual generation of a neural impulse to the brain from higher order neurones. It is already well known that the initial and primary process in vision is the absorption of photons by 1l-cis retinal and concomitant isomerisation of the visual pigment to all-trans retinal. We have therefore studied events resulting from this photoisomerisation, events which provide a link between the absorption of light and the excitation of the receptor cell.

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address for reprint requests: The Physiological Laboratory, Downing Street, University of Cambridge, Cambridge CB2 3EG.

References

  1. 1

    Yoshikami, S., and Hagins, W. A., Biophys. J. Abstr., 11, 47a (1971).

  2. 2

    Mason, W. T., Fager, R. S., and Abrahamson, E. W., Biochemistry, 12, 2147 (1973).

  3. 3

    Mason, W. T., and Lee, Y. F., Nature new Biol., 244, 143 (1973).

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Author notes

    • W. T. MASON

    Present address: The Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, CB2 3EG

Affiliations

  1. Department of Chemistry, Case Western Reserve University, Cleveland, Ohio, 44106

    • W. T. MASON
    • , R. S. FAGER
    •  & E. W. ABRAHAMSON

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https://doi.org/10.1038/247562a0

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