Abstract
THE administration of anticancer drugs in amounts necessary to obtain a therapeutic response can be associated with severe toxicity. Attempts to circumvent such toxicity have been made and examples of this include intra-arterial infusion chemotherapy and the administration of drugs directly into neoplastic lesions. We wish to suggest a novel extension of such regional cancer chemotherapy and to describe the use of aerosol dosing to confer protective antitumour effects in the lungs of mice carrying certain transplanted tumours.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Heyes, J., Catherall, E. J., and Harnden, M. R., 8th Int. Congr. Chemother. (1973).
Mitchell, R. I., Am. Rev. resp. Dis., 82, 627 (1960).
Bradish, C. J., Allner, K., and Maber, H. B., J. gen. Virol., 12, 141 (1971).
Parr, I., Wheeler, E., and Alexander, P., Br. J. Cancer, 27, 370 (1973).
Hellmann, K., and Burrage, K., Nature, 224, 273 (1969).
Wexler, H., J. natn. Cancer Inst., 36, 641 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HEYES, J., CATHERALL, E. Aerosol Chemotherapy of Lung Neoplasia. Nature 247, 485–487 (1974). https://doi.org/10.1038/247485a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/247485a0
This article is cited by
-
Use of vitamins, hormones, metabolites, and immunostimulators as antiblastomogenic substances
Pharmaceutical Chemistry Journal (1977)
-
Search for new antitumor agents among biopolymers and their synthetic analogs
Pharmaceutical Chemistry Journal (1976)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
