Letter | Published:

Survival of Unmodified Spleen Allografts in Rats

Naturevolume 247pages465466 (1974) | Download Citation

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Abstract

LABORATORY models which provide for reproducible acceptance of organ allografts with neither preoperative conditioning or postoperative immunosuppression of recipient animals are rare. In pigs, however, liver allografts are generally accepted even if histocompatibility differences are strong1–3; and indefinite acceptance of renal allografts in rats across major Ag-B barriers has been described4.

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References

  1. 1

    Calne, R. Y., White, H. J. O., Yoffa, D. E., Maginn, R. R., Binns, R. M., Samuel, J. R., and Molina, V. P., Brit. med. J., 2, 478 (1967).

  2. 2

    Calne, R. Y., Sells, R. A., Pena, J. R., Davis, D. R., Millard, P. R., Herbertson, B. M., Binns, R. M., and Davies, D. A. L., Nature, 223, 472 (1969).

  3. 3

    Peacock, J. H., and Terblanche, J., The Liver, 333 (Butterworths, London, 1967).

  4. 4

    Salaman, J. R., Transplantation, 11, 63 (1971).

  5. 5

    Bitter-Suermann, H., Transplantation (in the press).

  6. 6

    MacDonald, A. S., Davies, D. A. L., and Calne, R. Y., Transplant. Abstr.: Fourth Int. Transplant. Soc., 180 (Grune and Stratton, New York, 1972).

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Affiliations

  1. Department of Surgery, University of Cambridge

    • HINRICH BITTER-SUERMANN

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https://doi.org/10.1038/247465a0

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