Abstract
PAULING1 has suggested that a high intake of vitamin C may be necessary for optimum cerebral function including learning and memory. We have tested this hypothesis in a preliminary way by comparing maze learning in two groups of guinea pigs: those receiving large supplements of ascorbic acid (the ‘control’ group) and those receiving a daily quantity of the vitamin sufficient to maintain a concentration in the brain at approximately 25% that of the controls (the ‘deficient’ group).
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References
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Roe, J. H., and Kuether, C. A., J. biol. Chem., 147, 399 (1943).
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ADLARD, B., MOON, S. & SMART, J. Discrimination learning in ascorbic acid-deficient guinea pigs. Nature 247, 398 (1974). https://doi.org/10.1038/247398a0
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DOI: https://doi.org/10.1038/247398a0
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