Abstract
THE alveolar macrophage plays a crucial role in the pulmonary ecology and is a first line of cellular defence for the lung1,2. Although animal studies indicate that pulmonary macrophages originate from the bone marrow3–5, little is known of the origin or fate of these cells in man. Cigarette smokers, however, are known to have substantially increased numbers of macrophages in the lung1,6 and the pulmonary macrophages in smokers demonstrate characteristic morphologic and functional attributes1,2,7,8.
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GOLDE, D., BYERS, L. & FINLEY, T. Proliferative Capacity of Human Alveolar Macrophage. Nature 247, 373–375 (1974). https://doi.org/10.1038/247373a0
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DOI: https://doi.org/10.1038/247373a0
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