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Blue-Green Bacteria synthesise L-Tyrosine by the Pretyrosine Pathway

Naturevolume 247pages290292 (1974) | Download Citation



THE similarity of major biochemical pathways throughout the animal and plant kingdoms1 presumably reflects the ancient formation of the pathways in a common ancestral counterpart of modern cell types. The pathway previously known for L-tyrosine biosynthesis in both prokaryotie and eukaryotic microorganisms (Fig. 1a) involves a dehydrogenation-decarboxylation conversion of prephenate to 4-hydroxyphenylpyruvate followed by transamination in the presence of a suitable amino donor. Our data (Fig. 1b) demonstrate a reversed order of these two reactions in several species of blue–green algae (more appropriately designated bacteria (order Chrooeocales2)).

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  1. Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas, 77025

    •  & ROY A. JENSEN
  2. Department of Chemistry, Texas A and M University, College Station, Texas, 77843



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