Abstract
The rate of nucleotide change between globin genes for mouse, rabbit, rat and man is considerably slower than that of non-repeated DNA, suggesting that selection pressure is less stringent on the bulk of the genome than on genes coding for polypeptides.
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References
Kimura, M., Nature, 217, 624–626 (1968).
McCarthy, B. J., and Farquhar, M. N., Brookhaven Symp. Biol., 23, 1–42 (1971).
Britten, R. J., and Davidson, E. H., Science, N.Y., 165, 349–357 (1969).
Georgiev, G. P., J. theor. Biol., 25, 473–490 (1969).
Crick, F., Nature, 234, 25–27 (1971).
Paul, J., Nature, 238, 444–446 (1972).
Harrison, P. R., Hell, A., Birnie, G. D., and Paul, J., Nature, 239, 219–221 (1972).
Packman, S., Aviv, H., Ross, J., and Leder, P., Biochem. biophys. Res. Commun., 49, 813–819 (1972).
Bishop, J. O., Pemberton, R., and Baglioni, C., Nature new Biol., 235, 231–234 (1972).
Bishop, J. O., and Rosbash, M., Nature new Biol., 241, 204–207 (1973).
McConaughy, B. L., and McCarthy, B. J., Biochem. Genet., 4, 425–446 (1970).
Kohne, D. E., Q. Rev. Biophys., 33, 327 (1970).
Lockard, R. E., and Lingrel, J. B., J. biol. Chem., 247, 4174–4179 (1972).
Williamson, R., Morrison, M., Lanyon, G., Eason, R., and Paul, J., Biochemistry, 10, 3014–3021 (1971).
Aviv, H., and Leder, P., Proc. natn. Acad. Sci., U.S.A., 69, 1408–1412 (1972).
Adesnik, M., Salditt, M., Thomas, W., and Darnell, J. E., J. molec. Biol., 71, 21 (1972).
Kacian, D. L., Watson, K. F., Burny, A., and Spiegelman, S., Biochim. biophys. Acta, 246, 365–383 (1971).
Harrison, P. R., Birnie, G. D., Hell, A., Humphries, S., Young, B., and Paul, J., J. molec. Biol., (in the press).
Sutton, W. O., Biochim. biophys. Acta, 240, 522–531 (1971).
Britten, R. J., and Kohne, D. E., Science, N.Y., 161, 529–540 (1968).
Laird, C. D., McConaughy, B. L., and McCarthy, B. J., Nature, 224, 149–154 (1969).
Bollum, F. J., in Meth. in Enzymology, 12B, 591–611 (1968).
Dayhoff, M. O., Atlas of Protein Sequence and Structure D-53-54, (National Biomedical Research Foundation, Washington, DC, 1972).
Leder, P., Aviv, H., Gielen, J., Ikawa, Y., Packman, S., Swan, D., and Ross, J., Cold Spring Harb. Symp. quant. Biol., 38, (in the press).
Birnstiel, M. L., Weinberg, E. S., and Pardue, M. L., Gatlinburg Conference Proceedings, 173, (in the press).
Housman, D., Forget, B. F., Skoultchi, A., and Benz, E. J., Proc. natn. Acad. Sci., U.S.A., 70, 1809–1813 (1973).
Marotta, C., Verma, I. M., McCaffrey, R. P., and Forget, B. F., Fed. Proc., 32, 455 (1973).
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Gummerson, K., Williamson, R. Sequence divergence of mammalian globin messenger RNA. Nature 247, 265–267 (1974). https://doi.org/10.1038/247265a0
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DOI: https://doi.org/10.1038/247265a0
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