Abstract
THERE have been several outbreaks of a vesicular disease in swine in which the causative agent was shown to be an enterovirus1–3. The first occurred in Italy in 19661 and this was followed by an outbreak in Hong Kong in 19712. A more serious and widespread outbreak occurred in the United Kingdom during the winter of 1972-733 and several other cases were reported in Austria, France, Italy and Poland during the same period. Further cases also occurred in the United Kingdom in June 1973. From an epidemiological point of view it was important to know whether the same strain of virus had caused the disease in the different countries. Differences between some isolates could be demonstrated by complement fixation tests using specific antisera prepared in guinea pigs (Arrowsmith, A., personal communication) and by cross-neutralization tests using sera from convalescent swine (ref. 2 and R. B., Mann, J. A., and Goodridge, D., unpublished). We show here that unequivocal antigenic differences between some of the isolates can be demonstrated by immunodiffusion tests.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nardelli, L., Lodetti, E., Gualandi, G. L., Burrows, R., Good-ridge, D., Brown, F., and Cartwright, B., Nature, 219, 1275 (1968).
Mowat, G. N., Darbyshire, J. H., and Huntley, J. F., Vet. Rec., 90, 618 (1972).
Dawe, P. S., Forman, A. J., and Smale, C. J., Nature, 241, 540 (1973).
Graves, J. H., Nature, 245, 314 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BROWN, F., TALBOT, P. & BURROWS, R. Antigenic Differences between Isolates of Swine Vesicular Disease Virus and their Relationship to Coxsackie B5 Virus. Nature 245, 315–316 (1973). https://doi.org/10.1038/245315a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/245315a0
This article is cited by
-
Partial 3D gene sequences of Coxsackie viruses reveal interspecies exchanges
Virus Genes (2007)
-
Development of a real-time PCR assay based on primer-probe energy transfer for the detection of swine vesicular disease virus
Archives of Virology (2006)
-
Infective viruses produced from full-length complementary DNA of swine vesicular disease viruses HK/70 strain
Chinese Science Bulletin (2006)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.