Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Prostaglandin Production and Bone Resorption by Dental Cysts

Abstract

SEVERAL malignant tumours1–4 and benign dental cysts5 resorb bone in tissue culture. As prostaglandins can resorb bone6 and the mouse fibrosarcoma synthesizes PGE2-like material7, we studied the possibility that the resorption factor produced by dental cysts is a prostaglandin.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Goldhaber, P., Proc. Am. Assoc., Cancer Res., 3, 113 (1960).

    Google Scholar 

  2. Goldhaber, P., Roth, S. I., and Cirulis, G., Cancer Res., 24, 254 (1964).

    CAS  PubMed  Google Scholar 

  3. Goldhaber, P., J. dent. Res., 50, 278 (1971).

    Article  CAS  Google Scholar 

  4. Myers, W. P. L., Rothschild, E. O., Carney, V., Kaplan, N., Greenberg, E. J., Dimich, A., and Weber, D., Calc. Tiss. Res., 2, 63, Suppl. 63–4 (1968).

    Article  Google Scholar 

  5. Harris, M., and Goldhaber, P., Brit. J. oral Surg., 10, 349 (1973).

    Google Scholar 

  6. Klein, D. C., and Raisz, L. G., Endocrinology, 86, 1436 (1970).

    Article  CAS  Google Scholar 

  7. Levine, L., Hinkle, P. M., Voelkel, E. F., and Tashjian, A. H., Biochem. biophys. Res. Commun., 47, 888 (1972).

    Article  CAS  Google Scholar 

  8. Unger, W. G., Stamford, I. F., and Bennett, A., Nature, 233, 336 (1971).

    Article  ADS  CAS  Google Scholar 

  9. Vane, J. R., Brit. J. Pharmac. Chemother., 12, 344 (1957).

    Article  CAS  Google Scholar 

  10. Bennett, A., Stamford, I. F., and Unger, W. G., J. Physiol., 229, 349 (1973).

    Article  CAS  Google Scholar 

  11. Reynolds, J. J., Exp. Cell Res., 42, 178 (1966).

    Article  CAS  Google Scholar 

  12. Vane, J. R., Nature new Biol., 231, 232 (1971).

    Article  CAS  Google Scholar 

  13. Gréen, K., and Samuelsson, B., J. Lipid Res., 5, 117 (1964).

    PubMed  Google Scholar 

  14. Stamford, I. F., and Unger, W. G., J. Physiol., 225, 4P (1972).

    CAS  PubMed  Google Scholar 

  15. Jacobsen, N., and Goldhaber, P., J. dent. Res., 51, 1682 (1972).

    Article  CAS  Google Scholar 

  16. Eakins, K. E., Karim, S. M. M., and Miller, J. D., Brit. J. Pharmac., 39, 556 (1970).

    Article  CAS  Google Scholar 

  17. Bennett, A., and Posner, J., Brit. J. Pharmac., 42, 584 (1971).

    Article  CAS  Google Scholar 

  18. Zannelli, J. M., Lea, D. J., and Nisbet, J. A., J. Endocr., 43, 33 (1969).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

HARRIS, M., JENKINS, M., BENNETT, A. et al. Prostaglandin Production and Bone Resorption by Dental Cysts. Nature 245, 213–215 (1973). https://doi.org/10.1038/245213a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/245213a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing