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Anaerobic, Glycogen-dependent Transport of Amino Acids by the Placenta

Abstract

THE concentration of amino acids is greater in foetal than in maternal blood and their placental transport is fairly well established to depend on energy dependent processes1. Although it is reported that placental transport of amino acids occurs only in aerobic conditions2–4, we show here that the human placenta can accumulate amino acids anaerobically against a concentration gradient, and that this is sustained by the utilization of glycogen.

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LONGO, L., YUEN, P. & GUSSECK, D. Anaerobic, Glycogen-dependent Transport of Amino Acids by the Placenta. Nature 243, 531–533 (1973). https://doi.org/10.1038/243531a0

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