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A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas

Nature volume 242, pages 29–31 (1973)Cite this article

Abstract

An immunologically specific factor circulating in lymph and blood prevents the occurrence of lung metastases in rats with sarcomas growing in the leg. Removal of thoracic duct lymph causes such tumours to metastasize to the lung. This is due to the removal of a plasma factor and not of lymphocytes.

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Author information

Author notes

  1. C. M. RUDENSTAM

    Present address: Department of Surgery, University of Gothenburg, Sweden

Authors and Affiliations

  1. Chester Beatty Research Institute, Belmont, Sutton, Surrey

    J. W. PROCTOR, C. M. RUDENSTAM & P. ALEXANDER

Authors
  1. J. W. PROCTOR
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  2. C. M. RUDENSTAM
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  3. P. ALEXANDER
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PROCTOR, J., RUDENSTAM, C. & ALEXANDER, P. A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas. Nature 242, 29–31 (1973). https://doi.org/10.1038/242029a0

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