Abstract
CELL and tissue growth regulation occurs in response to specific stimuli. Bullough1,2 has shown that a number of tissues contain a saline-extractable, cell-specific substance, chalone, which can depress the mitotic activity of the corresponding cells in these tissues. He concluded that the presence of adrenaline and hydrocortisone was necessary in order to activate the chalone.
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References
Bullough, W. S., and Lawrence, E. B., Proc. Roy. Soc. Biol, 151, 517 (1960).
Bullough, W. S., Hewett, E. C., and Lawrence, E. B., Exp. Cell Res., 36, 192 (1964).
Bullough, W. S., and Lawrence, E. B., Nature, 220, 136 (1968).
Rytömaa, T., and Kivinierni, K., Nature, 220, 136 (1968).
Mohr, U., Althoff, J., Kinzel, V., Süss, R., and Volm, M., Nature, 220, 138 (1968).
Bichel, P., Europ. J. Cancer, 6, 291 (1970).
Bichel, P., Nature, 231, 449 (1971).
Heidnik, M. L., and Ryan, W. L., Cancer Research, 30, 376 (1970).
Clark, R. B., and Perkins, J. P., Proc. US Nat. Acad. Sci., 68, 2757 (1971).
Johnson, G. S., Friedman, R. M., and Pastan, I., Proc. US Nat. Acad. Sci, 68, 425 (1971).
Sheppard, J. R., Nature New Biology, 236, 14 (1972).
Stoker, M. G. P., Shearer, M., and O'Neill, C. J., Cell. Sci., 1, 297 (1966).
Burk, R. R., Wistar Inst. Symp. Monogr., 7, 39 (1967).
Burk, R. R., Nature, 219, 1272 (1968).
Schorr, I., Rathman, P., Saxena, B. B., and Ney, R. H., J. Biol Chem., 246, 5800 (1971).
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COOPER, P., SMITH, H. Influence of Cell-free Ascites Fluid and Adenosine 3′5′-Cyclic Monophosphate upon the Cell Kinetics of Ehrlich's Ascites Carcinoma. Nature 241, 457–458 (1973). https://doi.org/10.1038/241457a0
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DOI: https://doi.org/10.1038/241457a0
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