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Absence of JAK-2V617F point mutations in multiple myeloma

Leukemia volume 21, pages 813–814 (2007)Cite this article

Note: During the preparation of this manuscript for submission, we noticed a report of similar study from Dr Fiorini et al.9 Our results are consistent with their results and confirm the conclusion that JAK2 V617F mutation is very infrequent in human MM despite the fact that constitutional activation of JAK2 kinase as well as STAT3 phosphorylation is frequently seen in MM patients. So other mechanisms, different from JAK2 V617F mutation, could explain the pathogenesis of MM.

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  1. Division of Pathology, City of Hope National Medical Center, Duarte, CA, USA. E-mail: qhuang@coh.org,

    Q Huang, X Li, W Chen & L M Weiss

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Huang, Q., Li, X., Chen, W. et al. Absence of JAK-2V617F point mutations in multiple myeloma. Leukemia 21, 813–814 (2007). https://doi.org/10.1038/sj.leu.2404551

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