Figure 2 | Leukemia

Figure 2

From: Identification of a molecular signature for leukemic promyelocytes and their normal counterparts: focus on DNA repair genes

Figure 2

Hierarchical clustering trees of unsupervised and supervised analyses of leukemic and normal promyelocytes. (a) ‘Condition’ tree clustering computed using the Pearson correlation equation of unsupervised analysis (15 070 transcripts) defines two subclasses: APL promyelocytes and normal CD34+-derived promyelocytes from healthy donors; (b) Eisen tree map computed using the GeneSpring ‘gene’ and ‘condition’ trees and the Pearson correlation equation on the 1020 modulated transcripts identified by the supervised analyses. sAPLs, de novo APL and normal promyelocytes are shown in black, red and blue, respectively.

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