Main
In the paper entitled ‘The expression of immediate early gene X-1 (IEX-1) is differentially induced by retinoic acids in NB4 and KG1 cells: possible implication in the distinct phenotype of retinoic acid-responsive and -resistant leukemic cells’ we inadvertently assigned KG1 leukemic cells to a t(11;17) karyotype expressing the PLZF-RAR fusion protein. In fact, KG-1 cells do not express PLZF- and PML-RAR fusion proteins. Whatsoever, the findings on the differential induction of IEX-1 by retinoic acids in NB4 and KG1 cells are not affected by this mistake, because the distinct induction kinetics of IEX-1 found in these two cell lines relate to their distinct responsiveness in terms of proliferation, apoptosis and differentiation which is determined by PML-RAR (NB4) and its wild-type counterparts (KG1). Hence, retinoic acid induced IEX-1 expression in PML-RAR is transient and does not confer higher apoptotic sensitivity as observed in KG1 cells that persistently express IEX-1 upon retinoic acid treatment and become highly sensitive to apoptotic stimuli.
The authors apologize for these errors.
Additional information
The online version of the original article can be found at 10.1038/sj.leu.2403481
Rights and permissions
About this article
Cite this article
Arlt, A., Minkenberg, J., Kocs, B. et al. Erratum: Immediate early gene X-1 (IEX-1) is differentially induced by retinoic acids in NB4 and KG1 cells: possible implication in the distinct phenotype of retinoic acid-responsive and -resistant leukemic cells. Leukemia 20, 1651 (2006). https://doi.org/10.1038/sj.leu.2404347
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2404347