Figure 4 | Leukemia

Figure 4

From: Restoration of shp1 expression by 5-AZA-2′-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma

Figure 4

In vitro measurement of the NPM-ALK tyrosine kinase activity after 5-AZA treatment. 5-AZA did not significantly decrease the absorbance in Karpas 299 compared to the negative controls (treated with acetic acid only). AG490, which was previously shown to decrease the tyrosine kinase activity of NPM-ALK, served as a control.

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