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Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia

Leukemia volume 17, pages 981–983 (2003)Cite this article

TO THE EDITOR

The glutathione S-transferase (GSTs) superfamily of enzymes catalyzes the conjugation of xenobiotics and potentially damaging oxidative metabolites with glutathione. Four major subfamilies of GSTs (α, μ, π, θ) can be distinguished in humans.

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Figure 1

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Acknowledgements

This work was partially supported by grants from the Associazione Italiana per la Ricerca contro il Cancro (AIRC), Ministero Istruzione, Università, Ricerca Tecnologica (MIUR): Cofin 40% and ‘Oncologia Bridge’, Fondazione M. Tettamanti, Fondazione ‘Città della Speranza’. We thank Dr Andrea Callegaro for the help in statistical analyses.

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Authors and Affiliations

  1. Centro Ricerca M. Tettamanti, Clinica Pediatrica Universitá di Milano Bicocca, Monza, Italy

    Alessandra Sala, Carmelo Rizzari & Andrea Biondi

  2. Emato-Oncologia Pediatrica, Istituto Giannina Gaslini, Genova, Italy

    Marina Lanciotti, Paola di Michele, Carlo Dufour & Riccardo Haupt

  3. Istituto di Biometria e Statistica Universitá di Milano Bicocca, Monza, Italy

    Maria Grazia Valsecchi

  4. Emato-Oncologia Pediatrica, Università di Padova, Padova, Italy

    Giuseppe Basso

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  1. Alessandra Sala
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Sala, A., Lanciotti, M., Valsecchi, M. et al. Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia. Leukemia 17, 981–983 (2003). https://doi.org/10.1038/sj.leu.2402888

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  • DOI: https://doi.org/10.1038/sj.leu.2402888

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