(Landes Bioscience, Georgetown, Texas; 2001) Edited by Mikhail V Blagosklonny MD
There is little doubt that the field of cell cycle control, and its intimate links with cancer and biological responses to DNA damage, represent one of the most dynamic and fruitful areas of contemporary biomedical research. The value and emerging impact of this field is perhaps best documented by the fact that the Nobel prize for physiology and medicine this year has been awarded to acknowledge the seminal discoveries about the eukaryotic cell cycle, and their potential to be exploited in the ongoing war against cancer. Given the highly topical nature and rapid pace of new findings in this field, any attempt to summarize the recent major advances in cell cycle and cancer research is a valuable one, yet requires a very brave decision. The book on ‘Cell Cycle Checkpoints and Cancer’, edited by Mikhail Blagosklonny, is such a brave attempt, and a very successful one indeed. The editor himself is one of the recognized leading experts active in research at the border between cell cycle control, DNA damage checkpoints, and molecular oncogenesis. He succeeded in recruiting outstanding scientists in this field, to contribute a series of chapters on the key aspects of cell cycle checkpoints and their relevance to basic as well as applied oncological research.
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