Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Low-dose melphalan in elderly acute myeloid leukaemia: complete remissions but resistant relapse with therapy-related karyotypes

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Omoto E, Deguchi S, Takaba S, Kojima K, Yano T, Katayama Y, Sunami K, Takeuchi M, Kimura F, Harada M, Kimura I . Low-dose melphalan for treatment of high-risk myelodysplastic syndromes Leukemia 1996 10: 609–614

    CAS  PubMed  Google Scholar 

  2. Denzlinger C, Bowen D, Benz D, Gelly K, Brugger W, Kanz L . Low-dose melphalan induces favourable responses in elderly patients with high risk myelodysplastic syndromes or secondary acute myeloid leukaemia Br J Haematol 2000 108: 93–95

    Article  CAS  Google Scholar 

  3. Sandberg A, Abe S, Kowalczyk J, Zedgenidze A, Takeuchi J, Kakati S . Chromosomes and causation of human cancer and leukaemia. I. Cytogenetics of leukaemias complicating other diseases Cancer Genet Cytogenet 1982 7: 95–136

    Article  CAS  Google Scholar 

  4. Merlat A, Lai H, Sterkers Y, Demory H, Bauters F, Preudhomme C, Fenaux P . Therapy-related myelodysplastic syndrome and acute myeloid leukemia with 17p deletion. A report on 25 cases Leukemia 1999 13: 250–257

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kerr, R., Cunningham, J. & Bowen, D. Low-dose melphalan in elderly acute myeloid leukaemia: complete remissions but resistant relapse with therapy-related karyotypes. Leukemia 14, 953 (2000). https://doi.org/10.1038/sj.leu.2401762

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2401762

Search

Quick links