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A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid

Leukemia volume 11, pages 609–611 (1997)Cite this article

Abstract

A typical case of eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression is reported. The patient achieved complete remission after oral administration of all-trans retinoic acid without any exposure to cytotoxic agents. The facts strongly suggest that the genetic event occurred at the level of pluripotent stem cells.

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Authors and Affiliations

  1. Division of Hematology, Department of Internal Medicine, Shanghai Chang-Zheng Hospital, China

    R-Q Yu & S-D Jiang

  2. Laboratory of Molecular Biology, Shanghai Institute of Hematology, China

    W Huang, S-J Chen & Z Chen

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  1. R-Q Yu
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  2. W Huang
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  3. S-J Chen
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  4. S-D Jiang
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  5. Z Chen
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Yu, RQ., Huang, W., Chen, SJ. et al. A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid. Leukemia 11, 609–611 (1997). https://doi.org/10.1038/sj.leu.2400600

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  • DOI: https://doi.org/10.1038/sj.leu.2400600

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