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Metabolic Coupling, Ionic Coupling and Cell Contacts

Nature volume 235, pages 262–265 (1972)Cite this article

Abstract

Observations using electron microscopy and freeze-etching techniques show that both metabolic coupling and ionic coupling in fibroblasts are associated with the appearance of “gap” junctions.

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References

  1. Furshpan, E. J., and Potter, D. D., in Curr. Topics Develop. Biol., 3, 95 (1968).

    Article  CAS  Google Scholar 

  2. Loewenstein, W. R., Ann. NY Acad. Sci., 137, 441 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Bennett, M. V. L., Ann. NY Acad. Sci, 137, 509 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Payton, B. W., Bennett, M. V. L., and Pappas, G. D., Science, 166, 1641 (1969).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Reese, T. S., Bennett, M. V. L., and Feder, N., Anat. Rec., 169, 409 (1971).

    Google Scholar 

  6. Sheridan, J. D., J. Cell Biol., 45, 91 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Borek, C., Higashino, S., and Loewenstein, W. R., J. Membrane Biol., 1, 274 (1969).

    Article  CAS  Google Scholar 

  8. Subak-Sharpe, J. H., Burk, R. R., and Pitts, J. D., J. Cell Sci., 4, 353 (1969).

    CAS  PubMed  Google Scholar 

  9. Subak-Sharpe, J. H., Ciba Found. Symp. Homeostatic Regul., 276 (1969).

  10. Fujimoto, W. Y., and Seegmiller, J. E., Proc. US Nat. Acad. Sci., 65, 577 (1970).

    Article  ADS  CAS  Google Scholar 

  11. Ashkenazi, Y. E., and Gartler, S. M., Exp. Cell Res., 64, 9 (1971).

    Article  CAS  PubMed  Google Scholar 

  12. Littlefield, J. W., Nature, 203, 1142 (1964).

    Article  ADS  CAS  PubMed  Google Scholar 

  13. Stoker, M. G. P., J. Cell Sci., 2, 293 (1967).

    CAS  PubMed  Google Scholar 

  14. Friedmann, T., Seegmiller, J. E., and Subak-Sharpe, J. H., Nature, 220, 272 (1968).

    Article  ADS  CAS  Google Scholar 

  15. Revel, J. P., and Karnovsky, M. J., J. Cell Biol., 33, C7 (1967).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Moor, H., and Muhlethaler, K., J. Cell Biol., 17, 609 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Pinto da Silva, P., and Gilula, N. B., Exp. Cell Res. (in the press).

  18. Goodenough, D. A., and Revel, J. P., J. Cell Biol., 45, 272 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Chalcroft, J. P., and Bullivant, S., J. Cell Biol., 47, 49 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Johnson, R. G., J. Cell Biol., 47, 100a (1970).

    Google Scholar 

  21. Kolodny, G. M., Exp. Cell Res., 65, 313 (1971).

    Article  CAS  PubMed  Google Scholar 

  22. Pitts, J. D., Abstracts of Ciba Found. Symp. Growth Control in Cell Cultures, 16 (1970).

  23. Goshima, K., Exp. Cell Res., 65, 161 (1971).

    Article  CAS  PubMed  Google Scholar 

Download references

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Author notes

  1. NORTON B. GILULA

    Present address: Department of Anatomy, Harvard Medical School, Boston, Massachusetts, 02115

  2. O. RAYMOND REEVES

    Present address: Department of Zoology, Oxford University, Oxford

Authors and Affiliations

  1. Departments of Physiology–Anatomy and Zoology, University of California, Berkeley, California, 94720

    NORTON B. GILULA, O. RAYMOND REEVES & ALAN STEINBACH

Authors
  1. NORTON B. GILULA
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  2. O. RAYMOND REEVES
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  3. ALAN STEINBACH
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GILULA, N., REEVES, O. & STEINBACH, A. Metabolic Coupling, Ionic Coupling and Cell Contacts. Nature 235, 262–265 (1972). https://doi.org/10.1038/235262a0

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